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Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study

Atherosclerosis Jul 12, 2018

Geijselaers SLC, et al. - In this cross-sectional study, researchers tested the theory that greater carotid circumferential wall stress (CWS) was linked to poorer cognitive performance. Study participants included 722 individuals (60 ± 8 years, 55% men, 42.5% highly educated, blood pressure 137 ± 19/77 ± 11 mmHg, n=197 with type 2 diabetes) who were assessed neuropsychologically and had intima-media thickness (IMT) and interadventitial diameter (IAD) of the left common carotid artery at a plaque-free site measured via vascular ultrasound. They calculated lumen diameter from IMT and IAD. They also assessed cognitive domains ie, memory, executive function and attention, and processing speed. In this study, relatively highly educated individuals in late middle age with adequately controlled cardiovascular risk factors did not show any relationship between carotid CWS and cognitive performance.

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