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Cardiac implantable electronic devices with a defibrillator component and all-cause mortality in left ventricular assist device carriers: Results from the PCHF-VAD registry

European Journal of Heart Failure Aug 21, 2019

Cikes M, Jakus N, Claggett B, et al. - Researchers compared left ventricular assist device (LVAD) recipients receiving a cardiac implantable electronic device (CIED) with a defibrillator component (implantable cardioverter-defibrillator and cardiac resynchronization therapy with defibrillation, CIED-D) vs those without one, in terms of features. They evaluated if carrying such a device contiguously with an LVAD is related to outcomes. In the multicentre European PCHF-VAD registry, an analysis of 448 patients (mean age 52 ± 13 years, 82% male) was carried out. Other than CIED-D, the remaining significant risk factors of all-cause death were age, LVAD implant as redo surgery, number of ventricular arrhythmia episodes and use of vasopressors before LVAD. In an investigation accounting for all active CIED-Ds, including those implanted during LVAD support, a significantly better survival during LVAD support was observed in relation to carrying such a device.
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