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BMI and its association with death and the initiation of renal replacement therapy (RRT) in a cohort of patients with chronic kidney disease (CKD)

BMC Nephrology Aug 30, 2019

Wang Z, Zhang Z, Chan S, et al. - Researchers sought to determine how higher BMI is associated with mortality and RRT in preterminal CKD patients. They grouped 3,344 CKD patients, who were recruited from the CKD.QLD registry, based on BMI at time of consent—normal (BMI 18.5–24.9 kg/m2), overweight (BMI 25–29.9 kg/m2), mild obesity (BMI 30–34.9 kg/m2) and moderate obesity+ (BMI ≥ 35 kg/m2)—as defined by WHO criteria. Among these CKD patients, more than 80% were reported as overweight or obese. They observed a significant “protective” effect of higher BMI against death without RRT in males however, no significant relationship was noted among females. For predicting RRT, higher BMI was not a risk factor in either male or female patients with CKD.
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