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Beta-blockers, tachycardia and survival following sepsis- An observational cohort study

Clinical Infectious Diseases Jan 22, 2021

Guz D, Buchritz S, Guz A, et al. - Given the correlation of sepsis with excessive release of catecholamines which causes tachycardia and correlates with poor clinical outcome, researchers here examined if chronic beta blockers (BB) therapy is linked with better clinical outcomes in patients with sepsis admitted to internal medicine wards. In this single center, observational cohort study, they included a total of 1,186 patients. Using a propensity-score model for therapy with BB, patients were matched. Findings revealed association of chronic BB therapy with reduced mortality in patients hospitalized with sepsis in internal medicine wards showing absolute and relative tachycardia.

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