Kim MC, Ahn Y, Sim DS, et al. - This multicenter study was conducted in view of the existing controversy regarding the proper timing as well as indication of revascularization for a non‐culprit artery in patients experiencing ST‐segment elevation myocardial infarction (STEMI) and multivessel disease (MVD) without cardiogenic shock. Data for patients with STEMI and MVD without cardiogenic shock were examined at 3 years based on the percutaneous coronary intervention (PCI) approach: immediate multivessel revascularization (MVR) (n = 351), stepwise MVR (n = 510), and culprit‐only PCI (n = 1,142). All-cause mortality was assessed as the primary outcome. A lower risk of all‐cause death, especially in the high‐risk subgroup, was observed in relation to in‐hospital stepwise MVR, vs culprit‐only PCI or immediate MVR, in this study sample of patients with STEMI and MVD without cardiogenic shock.