Zhang J, Cao J, Zhang Y, et al. - Researchers used a nested case-control design including 599 first stroke cases and 599 matched controls to investigate the relation of baseline plasma zinc with the risk of the first stroke, and examine any possible effect modifiers in hypertensive patients. The study population was drawn from the China Stroke Primary Prevention Trial. The data presented in this work showed a significantly lower risk of first hemorrhagic stroke in those with plasma zinc ≥ 106.9 μg/dL vs candidates with baseline plasma zinc < 106.9 μg/dL (median). A significant inverse connection was observed between plasma zinc and first hemorrhagic stroke in this study population.