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Baseline high-sensitivity C-reactive protein predicts macrovascular and microvascular complications of type 2 diabetes: A population-based study

Annals of Nutrition and Metabolism May 01, 2018

Aryan Z, et al. - Researchers determined the predictive utility of high-sensitivity C-reactive protein (hs-CRP) for coronary heart disease (CHD) events and microvascular complications in patients with type 2 diabetes mellitus (T2DM), excluding individuals with unavailable data or hs-CRP >20 mg/L. Hazards ratio of each SD increment in baseline hs-CRP was 1.028, 1.025, 1.037, and 1.035 for CHD, diabetic neuropathy, diabetic retinopathy, and diabetic kidney disease, respectively. Overall, both of CHD events and microvascular complications were predicted by baseline hs-CRP in patients with T2D. Improved discrimination of all end points (CHD events, diabetic retinopathy, neuropathy, and diabetic kidney disease) was possible by the addition of hs-CRP to traditional risk factors of vascular complications of T2DM.
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