Paques M, Rossant F; Finocchio L, et al. -

 This study was attempted to examine directional optical coherence tomography (OCT) and flood-illumination adaptive optics ophthalmoscopy images to detect evidence of misaligned photoreceptors following macular edema. Researchers included nine patients having recovered a normal macular profile after macular edema due to retinal vein occlusion. Focal attenuations of the inner segment/outer segment and of the cone outer segment tips lines may be present on OCT after macular edema. It was considered that these areas may exhibit a strong directional variability by both OCT and adaptive optics ophthalmoscopy, implying that misaligned photoreceptor outer segments contribute to such features. The assessment of outer retinal damage following macular edema should thus take into account the optical Stiles–Crawford impact to disambiguate missing from misaligned cones.