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Associations of skeletal muscle mass, fat mass and mortality among men and among women with stage I-III colorectal cancer

Cancer Epidemiology, Biomarkers & Prevention Mar 11, 2020

van Baar H, Winkels RM, Brouwer JGM, et al. - Researchers performed this study among men and among women with stage I-III colorectal cancer (CRC), to examine the links of abdominal skeletal muscle mass index (SMI), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with overall mortality in this patient population. A median follow-up of 4.3 years was performed. In the restricted cubic splines analyses, the link of SMI and mortality was statistically significantly in a non-linear way among men, with lower SMI levels related to higher mortality. There was no link between SMI and mortality among women. SAT was found to be related to mortality in a non-linear fashion for males as well as for females, with lower SAT levels being related to higher mortality. Experts found no significant link of VAT with mortality in men nor women. Overall, in this sample of CRC patients, the observed links of abdominal skeletal muscle mass with mortality were not the same for men vs for women.
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