Gu X, Li Y, Chen S, et al. - Via involving six cohort studies in China with 267,500 candidates, researchers explored the relationship of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C ), high-density lipoprotein cholesterol (HDL-C), and triglyceride with stroke. Data reported that the median duration of follow-up varied from 6 to 19 years. Eight thousand seventy-two people developed stroke during 2,295,881 person-years. Findings suggested a positive association of TC, LDL-C, and triglyceride with ischemic stroke. It was noted that hemorrhagic stroke risk was higher when TC was lower than 120 mg/dL. There was no association between LDL-C and triglyceride with hemorrhagic stroke. When HDL-C was lower than 50 mg/dL, ischemic and hemorrhagic stroke risks could be higher.