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Association of first trimester maternal vitamin D, ferritin and hemoglobin level with third trimester fetal biometry: Result from cohort study on vitamin D status and its impact during pregnancy and childhood in Indonesia

BMC Pregnancy and Childbirth Apr 05, 2019

Judistiani RTD, et al. - The association between maternal vitamin D level in the first trimester and fetal biometry in the later stage of pregnancy was investigated with adjusted OR for other determinants like hemoglobin and ferritin level in a prospective cohort study of pregnant women began in four cities in West Java, Indonesia. They identified hypovitaminosis in 195 (96.06%) of 203 recruited women. The highest proportion of anemia was noted among women with insufficient vitamin D, while the highest proportion of low ferritin level was observed among women with normal vitamin D level. Biparietal diameter and abdominal circumference were noted to be significantly correlated with maternal serum vitamin D after adjustment with maternal age, pre-pregnancy body mass index, parity, serum ferritin level, and hemoglobin level. These findings emphasize the significance of sufficient maternal vitamin D level for improving fetal growth and development.
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