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Association of diagnostic coding‐based frailty and outcomes in patients with heart failure: A report from the veterans affairs health system

Journal of the American Heart Association Dec 11, 2020

Kohsaka S, Sandhu AT, Parizo JT, et al. - This study was attempted to assess if frailty is correlated with elevated admission and mortality risk in the setting of heart failure. Researchers conducted a retrospective cohort analysis including patients treated within the Veterans Affairs Health System who had International Classification of Diseases, Ninth Revision codes for heart failure on 2 or more dates over a 2‐year period. They applied the clinical variables identifiable in claims data, such as demographic variables and markers of physical and cognitive dysfunction, to distinguish individuals meeting the frailty phenotype. In the analysis, 163,085 patients (41.9%) with ejection fraction (EF) measurement were included in the present analysis (38.3% with reduced EF and 61.7% with preserved EF) among 388,785 extracted patients with the coding of heart failure between 2015 and 2018. The results of this study exhibited that the frailty based on diagnostic coding was associated with a particularly higher risk of mortality despite adjustment for known clinical variables. The data underscore the utility of nontraditional parameters in the prognostic assessment.

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