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Association of diabetes with outcomes in patients undergoing contemporary percutaneous coronary intervention: Pre-specified subgroup analysis from the randomized GLOBAL LEADERS study

Atherosclerosis Feb 17, 2020

Chichareon P, Modolo R, Kogame N, et al. - Given that diabetes was well recognized as a strong predictor for adverse outcomes after percutaneous coronary intervention (PCI), however, studies in the era of drug-eluting stent and potent P2Y12 inhibitors have shown contradictory outcomes, researchers evaluated ischemic and bleeding outcomes following contemporary PCI according to diabetic status. The sample consisted of 15,957 individuals undergoing PCI for stable or acute coronary syndrome in the GLOBAL LEADERS study with known baseline diabetic status. After PCI, diabetic patients had a higher risk of ischemic incidents than non-diabetic patients, whilst the risk of bleeding was similar. The two different antiplatelet strategies (experimental vs reference strategy) didn't affect the results of diabetic patients following PCI.
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