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Association of body mass index with mortality in patients with cardiogenic shock following acute myocardial infarction: A contemporary Danish cohort analysis

Cardiology Jul 25, 2021

Hermansen GF, Junker Udesen NL, Josiassen J, et al. - This retrospective analysis was undertaken to examine the relationship between BMI and 30-day mortality in patients with acute myocardial infarction complicated by cardiogenic shock (AMICS). Patients were split, based on the WHO classification, as normal weight BMI < 24.9 kg/m 2 (n = 453), overweight BMI 25–29.9 kg/m 2 (n = 391), obese class 1 BMI 30–34.9 kg/m 2 (n = 131), and obese class 2 + 3 BMI > 35 kg/m 2 (n = 42). More comorbidities such as diabetes, hypertension, and dyslipidemia were found to be present in obese patients vs those with normal weight. It was revealed that 30-day mortality did not differ between groups (normal weight 44%, overweight 38%, obese class 1 41%, and obese class 2 + 3 45% at 30 days; ns). Among patients with AMICS, 30-day mortality was not related to the BMI category. Therefore, experts found no evidence of an “obesity paradox” in this contemporary cohort comprising patients with AMICS in Denmark.

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