Association of blood pressure and risk of cardiovascular and chronic kidney disease in Hong Kong hypertensive patients
Hypertension Jul 23, 2019
Wan EYF, et al. - Researchers sought to determine the relationships between systolic blood pressure, cardiovascular disease, and chronic kidney disease in a population-based cohort of 267,469 adult patients with hypertension but without diabetes mellitus, cardiovascular disease, or chronic kidney disease. They evaluated the risks of cardiovascular disease and chronic kidney disease associated with systolic blood pressure by Cox regression using baseline and repeated systolic blood pressure (average of all systolic blood pressure measurements in the past 5 years) systolic blood pressure. Diagnosis of 29,500 cardiovascular disease and 30,993 chronic kidney disease events were made over 1.4 million person-years follow-up (median 6 years). The analysis suggested a higher risk for cardiovascular disease or chronic kidney disease among hypertensive patients with elevated repeated systolic blood pressure. This was observed independent of different characteristics. For poor health, a very low single measurement of systolic blood pressure is suggested to be a potential indicator, however, there appears no threshold for usual systolic blood pressure.
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