Kheirbek RE, et al. - In this retrospective, longitudinal cohort study of patients (born 1905–1935), researchers tested the hypothesis that atrial fibrillation (AF) incidence declines after age 90 years, and morbidity is compressed into a brief period at the end of life. They analyzed data from 1,062,610 octogenarians, 317,161 nonagenarians, and 3,572 centenarians and used Kaplan–Meier curves to estimate cumulative incidence of AF by age group. With aging, an increase was noted in AF incidence. Being a centenarian was found to be related to reduced incidence and compression of morbidity. A higher adjusted mortality rate was observed in patients with AF. However, in patients over 80 with an AF diagnosis, risk of mortality could be attenuated by using a regimen of anticoagulants and antiplatelets.