Chung J, Kim HL, Lim WH, et al. - Whether aortic pulse pressure (APP) reflecting aortic stiffness is involved in orthostatic hypotension development was investigated in this study of prospectively recruited 200 patients (age 64.3 ± 10.9 years, 62.5% men). Participants had undergone invasive coronary angiography (ICA). ICA revealed the presence of obstructive coronary artery disease in 156 patients (78.0%). A total of 58 patients (29.0%) were found to have orthostatic hypotension. Higher APP was detected in patients with orthostatic hypotension vs those without. In this study, a link was identified between APP and increased risk of orthostatic hypotension among patients undergoing ICA. A possible role of central aortic stiffness in the development of orthostatic hypotension was also suggested.