Vijayvargiya P, et al. - In this systematic review and meta-analysis, researchers evaluated the connection between gastric emptying and upper GI symptoms (UGI Sx), independent of treatment. Studies assessing the relationship between gastric emptying and nausea, vomiting, early satiety/postprandial fullness, abdominal pain and bloating were included. According to findings, significant associations were found between gastric emptying and nausea, vomiting, abdominal pain and early satiety/fullness for patients with UGI Sx; gastric emptying and early satiety/fullness in patients with diabetes; gastric emptying and nausea in patients with gastroparesis in evaluating studies using optimal gastric emptying test methodology. An association between optimally measured delayed gastric emptying and UGI Sx was supported in this analysis.