Chen YM, et al. - Authors evaluated the association between autophagy and inflammatory parameters in patients with rheumatoid arthritis (RA) receiving biologic therapy. They used immunoblotting to examine protein expression of LC3-II and p62 in peripheral blood mononuclear cells. The involvement of autophagy in RA pathogenesis is suggested by the elevated autophagy with significant correlation to inflammation. They noted a probable partial association of the effectiveness of biologic therapy to the downregulation of autophagy expression.