Hesler MC, Buya X, Catena V, et al. - All patients (n = 129) who underwent percutaneous cementoplasty of the acetabulum (PCA) in a comprehensive cancer center for an acetabular metastasis between January 2008 and December 2015 were incorporated in this study to assess the clinical, radiological and periprocedural characteristics related to the occurrence or worsening of acetabular fracture (OWAF) after PCA in cancer patients. An initial articular fracture was noted in 18 of 140 patients (12.9%). In 12/140 (8.6%) PCA, intra-articular cement leakage (IACL) was noted. A preexisting articular fracture was the only peculiarity correlated with IACL. Eighteen of the 111 patients with imaging follow-ups exhibited OWAF. The presence of cement filling (even incomplete) of all acetabular metastatic locations was the only characteristic auspicious of OWAF-free survival. Thus, in all areas influenced by acetabular metastases, injecting cement could limit OWAF. Since survival after PCA is not ignorable, finishing an inadequate first PCA could aid to conserve patients’ quality of life.