Bo Q, et al. - Via a cross-sectional observational study of 23 eyes from 20 subjects with polypoidal choroidal vasculopathy (PCV) taken from the data gathered from December 1, 2017, to September 1, 2018, the researchers reported the morphologic features of polypoidal lesions (first recognized as features of PCV) and their correlation with branching vascular networks (BVNs, a variant of type 1 neovascularization) in eyes with PCV using swept-source optical coherence tomographic angiography (SS-OCTA, uses a laser light source with a longer wavelength {1,060 nm}). A total of 23 eyes underwent imaging and were given a diagnosis of PCV. Forty-three polypoidal lesions were recognized by indocyanine green angiography, and all corresponded to the structures that looked like clusters of tangled vessels on SS-OCTA images. The SS-OCTA identified 16 tangled vascular structures that were not observed on indocyanine green angiography (ICGA). Branching vascular networks were discovered on SS-OCTA imaging in all eyes, however, ICGA could identify BVNs in only 17 of 23 eyes. Out of the 43 tangled vascular structures, 40 were found at the edge of a BVN and 3 were correlated with type 2 neovascularization. Hence, previously reported polypoidal lesions could seem as tangled vascular structures correlated with BVN or type 2 neovascularization in eyes with PCV undergoing SS-OCTA imaging. Moreover, the recognition of polypoidal lesions in subjects with PCV as neovascular tangles rather than actual polypoidal lesions or aneurysmal dilatations could help promote the perception of their pathogenesis and response to treatment.