Lin C, et al. - Authors attempted to examine the link between antidepressant prescription (including novel antidepressants) and the risk of nasopharyngeal cancer (NPC) in a population-based study using National Health Insurance Research Database. No correlation was discovered between NPC occurrence and antidepressant prescription. Findings illustrated that for all classes of antidepressants, antidepressant exposure, regardless of cumulative dose, had no notable effect on NPC incidence; the adjusted odds ratio of cumulative selective serotonin reuptake inhibitor exposure ≥336 defined daily dose was 1.18, and for tricyclic antidepressant exposure ≥336 defined daily dose was 1.18.