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Anterior segment optical coherence tomography angiography for iris vasculature in pigmented eyes

British Journal of Ophthalmology Aug 21, 2020

Ang M, Devarajan K, Tan ACS, et al. - In this prospective study, researchers compared anterior segment optical coherence tomography angiography (AS-OCTA) systems in delineating normal iris vessels and iris neovascularisation (NVI) in eyes with pigmented irides. Ten consecutive patients [median age was 28 (20–35) years, and 50% were female] with normally pigmented iris, had AS-OCTA scans with a described illumination technique, before using the same protocol in five eyes with NVI (clinical stages 1–3). Compared with spectral-domain OCTA, the swept-source OCTA was better able to delineate iris vessels in normally pigmented irides. Both AS-OCTA systems have identified NVI features based on its atypical configuration or location, but further improvements are required to allow for more precise objective, serial quantification for clinical use.

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