Munuera-Gifre E, Saez M, Juvinyà-Canals D, et al. - Researchers conducted this cross-sectional study to characterize the distribution of T2DM retinal lesions and ascertain if it is symmetrical between the two eyes, is random or follows a certain pattern. Study participants included T2DM patients who had been referred for an outpatients’ ophthalmology visit for diabetic retinopathy screening in primary healthcare. Using central projection non-mydriatic retinography, retinal photographic images were taken. Four thousand seven hundred seventy lesions were identified from among the 94 individuals involved in the analysis. According to findings, DR lesion distribution is neither homogeneous nor random but rather follows a determined pattern for microaneurysms/haemorrhages as well as hard exudates. This distribution means it is possible to identify the most vulnerable areas of the retina to metabolic alteration. The findings may be valuable in automated DR detection algorithms and in determining the underlying physiopathological vascular and non-vascular mechanisms that may explain these differences.