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Analysis of cytokine levels in tears and clinical correlations after intense pulsed light treating meibomian gland dysfunction

American Journal of Ophthalmology Sep 09, 2017

Liu R, et al. - A randomized, double-masked, controlled study is designed to examine the change from baseline of inflammatory markers in tears of dry eye disease (DED) subjects because of meibomian gland dysfunction (MGD) after IPL (intense pulsed light) treatment and meibomian gland expression (MGE) compared to sham treatment and the correlations with ocular surface parameters. The study outcomes recommend IPL can significantly decrease inflammatory markers in tears of patients suffering from DED because of MGD after IPL treatment. These outcomes indicate that IL-17A and IL-6 play roles in the pathogenesis of DED because of MGD, and the reduction of the inflammatory factors is consistent with the improvement of partial clinical symptoms and signs.
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