Nadin T, Wallis D, Holroyd CR, et al. - The prevalence and predictors of work impairment and disability were evaluated among axial spondyloarthritis (axSpA) patients attending a biologic therapy clinic. A single-centre, cross-sectional study was designed to include patients with axSpA treated with biologic therapy. Researchers examined work participation with the Work Productivity and Activity Impairment Questionnaire. They compared work outcomes (presenteeism, absenteeism, health-related job loss) for gender, time since diagnosis, smoking status and disease outcome measures. A total of 165 patients were included in the study (mean age 47.6 years, 75% male, 21% current smokers). Almost 1 in 6 (14.4%) reported axSpA related job loss in this group of axSpA patients on biologic therapy (mean age 47.6 years). Associations were found between axSpA-related work disability, absenteeism, presenteeism and poorer scores for patient-reported disease outcome measures. It was considered that strategies for improving work productivity should be directed towards those patients at risk of poor work outcomes. Additional data are required including details of the types of work that are most difficult with axSpA.