Aeschbacher S, Mongiat M, Bernasconi R, et al. - In a population-based sample of adults aged 25–41 years (young adults from the general population), researchers examined the link between the aldosterone-to-renin ratio (ARR) and various blood pressure (BP) indices. In all participants, conventional and 24-h BP recordings were collected. Measurements of direct renin concentration and plasma aldosterone concentration were also obtained. The study sample comprised 1,353 people, with mean age 37 years, 56% were women. Across gender-specific ARR quartiles, all BP indices were higher. For conventional, 24-h, sustained and masked hypertension, the multivariable adjusted odds ratio (95%CI) per 1-unit rise in log-transformed ARR were estimated to be 1.70 (1.17; 2.28), 1.29 (1.06; 1.56), 1.82 (1.33; 2.49), and 1.14 (0.94; 1.38), respectively. Findings revealed a strong link of ARR with conventional and ambulatory BP among young adults. In the development of hypertension, a very early occurrence of an aldosterone-driven phenomenon was suggested.