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Age-related differences in the noninvasive evaluation for possible coronary artery disease: Insights from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial

JAMA Nov 26, 2019

Lowenstern A, Alexander KP, Hill CL, et al. - Via involving participants (n = 10,003) from 193 sites across North America and comprising outpatients without known coronary artery disease (CAD) but with symptoms suggestive of CAD, researchers ascertained if the prognostic utility of anatomic compared with functional testing varies based on patient age. Between October 2018 and April 2019, data were analyzed. According to findings, older individuals with stable CAD symptoms are more likely to have a positive noninvasive test result and more coronary artery calcium. Nevertheless, the risk of CV death/MI was only associated with a positive functional test result. It is important to further explore age-specific approaches to noninvasive CAD evaluation.
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