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Age and gender differences in ischemic stroke treatment in a nationwide analysis of 1.11 million hospitalized cases

Stroke Nov 03, 2019

Weber R, Krogias C, Eyding J, et al. - Utilizing a complete analysis of all German hospitalized patients with ischemic stroke, researchers examined age- and sex-related differences in access to stroke unit treatment, and use of intravenous thrombolysis (IVT) and mechanical thrombectomy (MT). Study participants were subdivided into six predefined age groups (20–44, 45–59, 60–69, 70–79, 80–89, and > 90 years). Using a random-effects model, pooled overall and age group estimates were calculated. There were 1,112,570 patients hospitalized from 2013 to 2017 for first or recurrent ischemic stroke. Overall, stroke unit treatment raised significantly from 66.8% in 2013 to 73.5% in 2017, as did IVT (from 12.4% to 15.9%) and MT (from 2.4% to 5.8%). Although the difference was reduced over time, treatments were still received by patients ≥ 80 years of age significantly less often. In both older patients and women of all ages, access to the stroke unit treatment must be increased. While there was no sex difference in IVT use, the significantly higher frequency of MT in women with ischemic stroke regardless of age is important to further investigate.

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