Kumar A, Sammour Y, Reginauld S, et al. - Researchers compared patients who received percutaneous coronary intervention (PCI) prior to transcatheter aortic valve replacement (TAVR) vs those who received PCI with/after TAVR, focusing on the rates of major adverse cardiovascular and cerebrovascular events (MACCE) in this multicenter study. For this purpose, all consecutive patients who had TAVR at three high volume centers were pooled. Overall, among patients who received both PCI and TAVR (n = 380), history of previous CABG, higher BMI at TAVR, and statin therapy post-TAVR were identified to be independently related to lower MACCE while warfarin therapy post-TAVR was shown to be related to a higher risk of MACCE. Irrespective of timing of PCI, the observed adverse events rates were similar.