Jentzer JC, van Diepen S, Murphree DH, et al. - Given that death risk among cardiac intensive care unit (CICU) patients can be stratified by critical care risk scores, but there exists uncertainty regarding risk score performance across common CICU admission diagnoses, so, researchers assessed performance of the Acute Physiology and Chronic Health Evaluation (APACHE)-III, APACHE-IV, Sequential Organ Failure Assessment (SOFA) and Oxford Acute Severity of Illness Score (OASIS) scores at the time of CICU admission in common CICU admission diagnoses. For this purpose, they utilized a database including 9,898 unique CICU patients admitted between 2007 and 2015. In each admission diagnosis, the mortality discrimination by each risk score was identified to be comparable, although experts reported that calibration was variable and best with APACHE-III. Among patients suffering from acute coronary syndromes and those with heart failure, the c-statistic values for each score were estimated to be 0.85-0.86 and 0.76-0.79, respectively. Overall, inconsistent performance of the examined risk scores was revealed for mortality risk stratification across admission diagnoses in this CICU population. These findings highlight the requirement to construct better tools for death risk prediction in critically-ill CICU patients.