Michail M, Hughes AD, Comella A, et al. - Researchers determined immediate alterations in invasively assessed left ventricular and central aortic pressure following transcatheter aortic valve replacement (TAVR) among patients experiencing severe aortic stenosis using aortic reservoir pressure, wave intensity analysis, as well as indices of aortic function. This analysis included 54 patients (mean age 83.6 ± 6.2 years, 50.0% female) undergoing TAVR. Post-TAVR, rises in systolic, diastolic, mean, and pulse aortic pressures were evident. After TAVR, no change was evident in reservoir pressure whereas 47% rise in excess pressure was detected. Increased forward compression wave, backward compression wave and forward expansion wave energies were shown by wave intensity analysis. Overall, raised central aortic pressure post-TAVR was shown to be associated with increased transmitted power and energy to the proximal aorta with raised excess pressure but unaltered reservoir pressure. These alterations afford a potential mechanism for the improved prognosis related to relative hypertension following TAVR.