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Active and passive case-finding in tuberculosis-affected households in Peru: A 10-year prospective cohort study

The Lancet Infectious Diseases May 01, 2019

Saunders MJ, et al. - Researchers identified index patients with tuberculosis and followed up contacts aged 15 years or older for tuberculosis in shanty towns in Callao, Peru, in order to evaluate the contribution of active vs passive case-finding to tuberculosis detection among contacts. Further, they compared sex and disease characteristics between contacts diagnosed through these strategies. As per findings, active case-finding makes a significant contribution to tuberculosis detection among contacts, however, most of the tuberculosis burden is detected with passive case-finding. Passive case-finding and active case-finding were identified as equitable. These two strategies assisted diagnosing tuberculosis earlier and usually before a positive result on sputum smear microscopy. Findings suggest a high burden of undetected tuberculosis among women.
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