Sia CH, et al. - In this investigation, researchers characterized the effect of demographic and anthropometric factors on electrocardiogram (ECG) variables and established a set of electrocardiographic reference ranges specific to a young male multiethnic Southeast Asian cohort. For this analysis, 144,346 young male conscripts had pre-participation screening that included a 12-lead ECG, demographic and anthropometric measurements between November 1, 2009, and December 31, 2014. Findings revealed that systolic blood pressure of >140 mmHg or diastolic blood pressure of >90 mmHg independently raised the prevalence of increased QRS voltage on ECG. According to results, electrocardiographic parameters differ across different ethnicities and in comparison with international norms. Diagnosis of increased QRS voltage by ECG was less prevalent with obesity and increased body fat in the study population. To enhance the precision of the ECG screening method, further evaluation of gold standard measurements for the diagnosis of LVH in the population is ongoing.