A new biomechanical glaucoma factor to discriminate normal eyes from normal pressure glaucoma eyes
Acta Ophthalmologica Nov 03, 2019
Pillunat KR, et al. - In this prospective cross-sectional multicentre pilot study, researchers developed and tested the new Dresden biomechanical glaucoma factor (DBGF) based on DCR parameters and corneal thickness, for the ability to separate healthy eyes from eyes of patients suffering from normal pressure glaucoma (NPG). Included were the eyes of 70 healthy controls and 70 NPG patients of Caucasian origin. Using 5 Corvis ST parameters, the DBGF was calculated, showing the best discrimination power: progression of the deformation amplitude ratio, highest concavity time, pachymetry slope, intraocular pressure and pachymetry corrected biomechanically. According to findings, the DBGF is sensitive and specific in order to discriminate healthy from the eyes of NPG. Since NPG diagnosis is often difficult, the DBGF can aid in everyday clinical practice with the differential diagnosis of NPG. It may, therefore, be considered as a possible new method of screening for NPG.
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