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A negative T‐wave in electrocardiogram at 50 years predicted lifetime mortality in a random population‐based cohort

Clinical Cardiology Sep 16, 2020

Sjöland H, Fu M, Caidahl K, et al. - Given that there exists a correlation of severe electrocardiographic (ECG) abnormalities with cardiovascular risk in asymptomatic individuals, researchers examined the correlation between a negative T‐wave in resting ECG and death during 48 years of follow‐up, in this longitudinal population‐based observational cohort analysis of 50‐year old men. Significantly higher blood pressure was detected in participants (n = 839) with a negative T‐wave (7.3%). Raised risk for all‐cause and cardiovascular (CV) mortality was noted in correlation with a negative T‐wave. Following removal of coexisting Q/QS patterns and ST‐junction/segment depression ECG abnormalities, the link remained. Mortality from other reasons was not related to a negative T‐wave. Overall, a raised risk of all‐cause and CV death during lifetime follow‐up was seen in asymptomatic individuals who had a negative T‐wave at 50 years.

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