Although populations in countries in the Global South are on average younger than in Europe, they might be more vulnerable to severe forms of COVID-19. One reason for this is the higher proportion of people at working age with pre-existing chronic conditions.

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At almost every age within this population group, more people in Brazil and Nigeria suffer from pre-existing chronic conditions than in European countries, such as Italy. This increases their risk of a severe case of COVID-19. "We show that the prevalence of cardiovascular diseases, chronic obstructive pulmonary disease, and chronic kidney disease in Brazil and Nigeria is considerably higher relative to Italy," said Marília Nepomuceno. The researcher at the Max Planck Institute for Demographic Research in Rostock, Germany, used data from the Global Burden of Disease Database for her analysis.

The results show that the proportion of people with cardiovascular diseases in their early 20s is more than two times higher in Brazil and Nigeria compared to Italy. For chronic kidney disease and chronic obstructive pulmonary disease, the prevalence in Brazil and Nigeria is also considerably greater relative to Italy. It is particularly higher for people over the age of 40. Among women, for instance, differences in prevalence can be up to four times higher in Nigeria than in Italy. These health disadvantages, which are common in the Global South, suggest that their working-age populations are far more vulnerable to severe forms of COVID-19 disease than that of Europe.